BlueCross BlueShield of Tennessee Medical Policy Manual

Liposuction and Lipectomy for Lipedema

DESCRIPTION

Lipedema is a rare disorder of adipose tissue of the extremities that primarily affects females and can be misdiagnosed as obesity or lymphedema. The cause is unknown; however, it is associated with hormonal and hereditary influences. It is a distinct entity that can be differentiated from obesity and lymphedema, although it can also progress to involve the venous and lymphatic systems increasing the difficulty of diagnosis. In most cases, lipedema affects the lower extremities, leaving ankle and feet unaffected with minimal pitting edema resembling “stovepipe” enlargement of the legs with a sharp demarcation between normal and abnormal tissue at the top of the ankle, referred to as the “cuff sign.” Lipedema isolated to the arms without involvement of the legs is extremely rare.

First-line treatment for lipedema is conservative therapy (i.e., exercise, dietary counseling, and psychosocial therapy) to reduce severity of symptoms. Liposuction or lipectomy may be considered to permanently remove subcutaneous fat deposits and reduce pain, and un-restrict movement to improve quality of life.

NOTE: Lipectomy is a benefit contract exclusion when performed as a cosmetic service.

POLICY

MEDICAL APPROPRIATENESS

IMPORTANT REMINDERS

ADDITIONAL INFORMATION

There are several distinct differences between the presentation of lipedema and primary lymphedema which are provided in the table below:

Lipedema

Lymphedema

Symmetric (buttocks involved)

Not symmetric

Foot not involved

Foot involved

Not pitting

Pitting edema

Stemmer sign negative

Stemmer signs positive

Tissue feels rubbery

Tissue feels firmer (starting stage 2 lymphedema)

Painful to touch

Generally, not painful to touch

Easy bruising

Generally, not bruising

Hormonal disturbances frequent

Generally, no hormonal disturbance

SOURCES

BlueCross BlueShield Association. Evidence Positioning System. (2:2024). Liposuction for Lipedema and Lymphedema. (7.01.169). Retrieved September 11, 2024 from https://www.bcbsaoca.com/eps/. (18 articles and/or guidelines reviewed)

Dadras, M., Mallinger, PJ., Corterier, CC., Theodosiadi, S., & Ghods, M. (2017). Liposuction in the treatment of lipedema: A longitudinal study. Archives of Plastic Surgery, 44 (4): 324-331. (Level 4 evidence)

Kruppa, P., Lakovos, M.D., Schmidt, J., Infanger,M., & Ghods, M. (2022). A 10-year retrospective before – and – after study of lipedema surgery: patient – reported lipedema-associated symptom improvement after multistage liposuction. Journal of the American Society of Plastic Surgeons, 149 (3), 529e-541e. Abstract retrieved from https://journals.lww.com/plasreconsurg/Abstract/2022/03000/A_10_Year_Retrospective_before_and_after_Study_of.43.aspx.

National Institute for Health and Care Excellence. (2022, March). Liposuction for chronic lipoedema. Retrieved March 1, 2023 from https://www.nice.org.uk/.

National Library of Medicine. (2019, June). Liposuction for the treatment of lipedema: A review of clinical effectiveness and guidelines. Retrieved March 1, 2023 from https://www.ncbi.nlm.nih.gov/.

Podda, M., Kovacs, M., Hellmich, M., Roth, R., Zarrouk, M., Kraus, D., et al. (2021). A randomised controlled multicentre investigator-blinded clinical trial comparing efficacy and safety of surgery versus complex physical decongestive therapy for lipedema (LIPLEG). Trials, 22 (758) https://doi.org/10.1186/s13063-021-05727-2. (Level 1 evidence)

Schmidt, J., Kruppa, P., Georgiou, L., & Ghods, M. (2021). Management of large volume liposuction in lipedema patients with von Willebrand disease: A systematic review and treatment algorithm. Clinical Hemorheology and Microcirculation, 78 (3), 311–324. Abstract retrieved March 1, 2023 from PubMed database.

Shavit, E., Wollina, U., & Alavi, A. (2018). Lipoedema is not lymphoedema: a review of current literature. International Wound Journal, 15 (6), 857-1053. (Level 5 evidence)

Van de Pas, CB., Boonen, R.SM., Stevens, S., Willemsen S., Valkema, R., & Neumann, M. (2019). Does tumescent liposuction damage the lymph vessels in lipoedema patients? Phlebology, 35 (4), 221-291. (Level 5 evidence)

Winifred S. Hayes, Inc. Evolving Evidence Review. (2022, April; last update search March 2024). Liposuction for the treatment of lipedema. Retrieved September 11, 2024 from www.hayesinc.com/subscribers. (21 articles and/or guidelines reviewed)

Wounds UK. (2017, March). Best practice guidelines: the management of lipoedema. Retrieved March 6, 2023 from https://www.wounds-uk.com/resources/details/best-practice-guidelines-management-lipoedema.

ORIGINAL EFFECTIVE DATE:  8/1/2023

MOST RECENT REVIEW DATE:  10/10/2024

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Policies included in the Medical Policy Manual are not intended to certify coverage availability. They are medical determinations about a particular technology, service, drug, etc. While a policy or technology may be medically necessary, it could be excluded in a member's benefit plan. Please check with the appropriate claims department to determine if the service in question is a covered service under a particular benefit plan. Use of the Medical Policy Manual is not intended to replace independent medical judgment for treatment of individuals. The content on this Web site is not intended to be a substitute for professional medical advice in any way. Always seek the advice of your physician or other qualified health care provider if you have questions regarding a medical condition or treatment.

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